Generation of a human iPSC line (MPIi008-A) from a patient with Denys-Drash syndrome

An induced pluripotent stem cell (hiPSC) line (MPIi008-A) was generated from fibroblasts of a 1-year-old male patient with Denys-Drash syndrome using lentiviral delivery of reprogramming factors OCT4, SOX2, KLF4 and c-MYC. The MPIi008-A iPSC line exhibited typical iPSC morphology and normal karyotyp...

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Bibliographic Details
Main Authors: Markus C. Doeser, Julia Krygin, Albrecht Röpke, Dong Han, Roland Wedlich-Söldner, Hans R. Schöler, Hermann Pavenstädt, Kee-Pyo Kim
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506122001751