The safety and efficacy of antifibrinolytic therapy in neonatal cardiac surgery.

Neonates undergoing open-heart surgery are particularly at risk of postoperative bleeding requiring blood transfusion. Aprotinin has attained high efficacy in reducing the requirement for a blood transfusion following a cardiopulmonary bypass, but is seldom studied in the neonatal age group. The aim...

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Bibliographic Details
Main Authors: Chih-Yuan Lin, Jeffery H Shuhaiber, Hugo Loyola, Hua Liu, Pedro Del Nido, James A DiNardo, Frank A Pigula
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4425500?pdf=render