Hydroxyethylamide substituted triterpenoic acids hold good cytotoxicity for human tumor cells

Pentacyclic triterpenoic acids, betulinic acid, platanic acid, oleanolic acid and ursolic acid, were acetylated and subsequently converted into mono-, bis- and tris(hydroxyl)ethyl amides. While parent compounds are of none or minor cytotoxicity, these amides showed EC50 values even in low μM concent...

Full description

Bibliographic Details
Main Authors: Toni C. Denner, Sophie Hoenke, Oliver Kraft, Hans-Peter Deigner, Ahmed Al-Harrasi, René Csuk
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Results in Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221171562200090X