Identifying actionable druggable targets for breast cancer: Mendelian randomization and population-based analysesResearch in context

Summary: Background: Drug repurposing provides a cost-effective approach to address the need for breast cancer prevention and therapeutics. We aimed to identify actionable druggable targets using Mendelian randomization (MR) and then validate the candidate drugs using population-based analyses. Met...

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Bibliographic Details
Main Authors: Naiqi Zhang, Yanni Li, Jan Sundquist, Kristina Sundquist, Jianguang Ji
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396423004255