Local and global influences on protein turnover in neurons and glia

Regulation of protein turnover allows cells to react to their environment and maintain homeostasis. Proteins can show different turnover rates in different tissue, but little is known about protein turnover in different brain cell types. We used dynamic SILAC to determine half-lives of over 5100 pro...

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Bibliographic Details
Main Authors: Aline R Dörrbaum, Lisa Kochen, Julian D Langer, Erin M Schuman
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/34202