Pharmacodynamic modeling of moderate sedation and rationale for dosing using midazolam, propofol and alfentanil

Abstract Purpose Regulations have broadened to allow moderate sedation administration for gastrointestinal endoscopy by non-anesthesia personnel. The line between moderate and deep sedation is ambiguous. Deep sedation offers patient comfort as well as greater safety concerns. Unintended deep sedatio...

Full description

Bibliographic Details
Main Authors: Jing-Yang Liou, I-Ting Kuo, Weng-Kuei Chang, Chien-Kun Ting, Mei-Yung Tsou
Format: Article
Language:English
Published: BMC 2023-01-01
Series:BMC Pharmacology and Toxicology
Subjects:
Online Access:https://doi.org/10.1186/s40360-023-00642-5