Cancer cells exhibit clonal diversity in phenotypic plasticity

Phenotypic heterogeneity in cancers is associated with invasive progression and drug resistance. This heterogeneity arises in part from the ability of cancer cells to switch between phenotypic states, but the dynamics of this cellular plasticity remain poorly understood. Here we apply DNA barcodes t...

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Bibliographic Details
Main Authors: Robert Austin Mathis, Ethan S. Sokol, Piyush B. Gupta
Format: Article
Language:English
Published: The Royal Society 2017-01-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.160283