Cancer cells exhibit clonal diversity in phenotypic plasticity
Phenotypic heterogeneity in cancers is associated with invasive progression and drug resistance. This heterogeneity arises in part from the ability of cancer cells to switch between phenotypic states, but the dynamics of this cellular plasticity remain poorly understood. Here we apply DNA barcodes t...
Main Authors: | Robert Austin Mathis, Ethan S. Sokol, Piyush B. Gupta |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2017-01-01
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Series: | Open Biology |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.160283 |
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