Sustained developmental endothelial locus-1 overexpression promotes spinal cord injury recovery in mice through the SIRT1/SERCA2 signaling pathway

Although the anti-inflammatory properties of developmental endothelial locus-1 (DEL-1) are well known, few studies have examined the role of DEL-1 in spinal cord injury (SCI). Here, the protective effect of DEL-1 on SCI was investigated using hypoxia/recovery (H/R) injury of astrocytes and a mouse S...

Full description

Bibliographic Details
Main Authors: Ming Cheng, Hongxin Wang, Guang Yang, Yuanchi Cheng, Zhen Yang, Xuyi Chen, Yingfu Liu, Zhonglei Sun
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Brain Research Bulletin
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923022000181