Sustained developmental endothelial locus-1 overexpression promotes spinal cord injury recovery in mice through the SIRT1/SERCA2 signaling pathway

Sustained developmental endothelial locus-1 overexpression promotes spinal cord injury recovery in mice through the SIRT1/SERCA2 signaling pathway

Although the anti-inflammatory properties of developmental endothelial locus-1 (DEL-1) are well known, few studies have examined the role of DEL-1 in spinal cord injury (SCI). Here, the protective effect of DEL-1 on SCI was investigated using hypoxia/recovery (H/R) injury of astrocytes and a mouse S...

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Bibliographic Details
Main Authors:	Ming Cheng, Hongxin Wang, Guang Yang, Yuanchi Cheng, Zhen Yang, Xuyi Chen, Yingfu Liu, Zhonglei Sun
Format:	Article
Language:	English
Published:	Elsevier 2022-04-01
Series:	Brain Research Bulletin
Subjects:	DEL-1 SIRT1/SERCA2 Spinal cord injury Hypoxia/recovery injury Endoplasmic reticulum stress Apoptosis
Online Access:	http://www.sciencedirect.com/science/article/pii/S0361923022000181

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