Lung Fibrosis Is Improved by Extracellular Vesicles from IFNγ-Primed Mesenchymal Stromal Cells in Murine Systemic Sclerosis

Background: Systemic sclerosis (SSc) is a severe autoimmune disease for which mesenchymal stromal cells (MSCs)-based therapy was reported to reduce SSc-related symptoms in pre-clinical studies. Recently, extracellular vesicles released by MSCs (MSC-EVs) were shown to mediate most of their therapeuti...

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Bibliographic Details
Main Authors: Pauline Rozier, Marie Maumus, Alexandre Thibault Jacques Maria, Karine Toupet, Christian Jorgensen, Philippe Guilpain, Danièle Noël
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/10/2727