Causal network inference from gene transcriptional time-series response to glucocorticoids.

Gene regulatory network inference is essential to uncover complex relationships among gene pathways and inform downstream experiments, ultimately enabling regulatory network re-engineering. Network inference from transcriptional time-series data requires accurate, interpretable, and efficient determ...

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Bibliographic Details
Main Authors: Jonathan Lu, Bianca Dumitrascu, Ian C McDowell, Brian Jo, Alejandro Barrera, Linda K Hong, Sarah M Leichter, Timothy E Reddy, Barbara E Engelhardt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1008223