Effect of JAK inhibitors on the three forms of bone damage in autoimmune arthritis: joint erosion, periarticular osteopenia, and systemic bone loss

Effect of JAK inhibitors on the three forms of bone damage in autoimmune arthritis: joint erosion, periarticular osteopenia, and systemic bone loss

Abstract Background The types of bone damage in rheumatoid arthritis (RA) include joint erosion, periarticular osteoporosis, and systemic osteoporosis. Janus kinase (JAK) inhibitors ameliorate inflammation and joint erosion in RA, but their effect on the three types of bone loss have not been report...

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Bibliographic Details
Main Authors: Masatsugu Komagamine, Noriko Komatsu, Rui Ling, Kazuo Okamoto, Shi Tianshu, Kotaro Matsuda, Tsutomu Takeuchi, Yuko Kaneko, Hiroshi Takayanagi
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Inflammation and Regeneration
Subjects:
JAK inhibitor
Autoimmune arthritis
Bone damage
Osteoclast
Osteoblast
Online Access:https://doi.org/10.1186/s41232-023-00293-3

Internet

https://doi.org/10.1186/s41232-023-00293-3

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