Gout management using uricase and sodium citrate hollow mesoporous nanomotors
Abstract Uricase (UOx)-based gout treatments are generally limited due in part to the accumulation of H2O2 in an arthrosis environment characterized by a sluggish metabolism. Here we develop a self-cascade nanomotor with high efficiency toward simultaneous uric acid (UA) degradation and H2O2 elimina...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-03-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-56100-9 |