GNPNAT1 is a potential biomarker correlated with immune infiltration and immunotherapy outcome in breast cancer

GNPNAT1 is a potential biomarker correlated with immune infiltration and immunotherapy outcome in breast cancer

BackgroundGlucosamine 6-phosphate N-acetyltransferase (GNPNAT1) is a crucial enzyme involving hexosamine biosynthesis pathway and is upregulated in breast cancer (BRCA). However, its biological function and mechanism on patients in BRCA have not been investigated.MethodsIn this study, the differenti...

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Bibliographic Details
Main Authors: Renjie Yuan, Yulu Zhang, Yange Wang, Hongling Chen, Ruiming Zhang, Zhiyuan Hu, Chengsen Chai, Tingmei Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
GNPNAT1
breast cancer
biomarker
tumor-infiltration immune cells
immune checkpoints inhibitors
immunotherapy response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1152678/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1152678/full

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