Response of Brain and Meningeal Metastases to Trastuzumab-Deruxtecan in a Patient with HER2-Low Breast Cancer: A Case Report

Response of Brain and Meningeal Metastases to Trastuzumab-Deruxtecan in a Patient with HER2-Low Breast Cancer: A Case Report

Nervous system metastases (CNSm) are late events associated with poor outcomes in endocrine-sensitive HER2-negative breast cancer (BC) patients, especially in the presence of leptomeningeal disease (LMD). Effective treatments are extremely limited in this setting. The antibody-drug conjugate, trastu...

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Bibliographic Details
Main Authors: Benita Wolf, Vincent Dunet, Estelle Dubruc, Ana Dolcan, Marie Nicod Lalonde, Luis Schiappacasse, Khalil Zaman
Format: Article
Language:English
Published: Karger Publishers 2023-11-01
Series:Case Reports in Oncology
Subjects:
brain metastases
leptomeningeal disease
her2-low
trastuzumab-deruxtecan
case report
Online Access:https://beta.karger.com/Article/FullText/534572

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https://beta.karger.com/Article/FullText/534572

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