Klebsiella pneumoniae OmpR facilitates lung infection through transcriptional regulation of key virulence factors

Klebsiella pneumoniae OmpR facilitates lung infection through transcriptional regulation of key virulence factors

ABSTRACT Bacteria must adapt to the stresses of specific environmental conditions to survive. This adaptation is often achieved by altering gene expression through two-component regulatory systems (TCSs). In Gram-negative bacteria, the response to environmental changes in osmolarity and pH is primar...

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Bibliographic Details
Main Authors: Axel B. Janssen, Vincent de Bakker, Rieza Aprianto, Vincent Trebosc, Christian Kemmer, Michel Pieren, Jan-Willem Veening
Format: Article
Language:English
Published: American Society for Microbiology 2024-01-01
Series:Microbiology Spectrum
Subjects:
Klebsiella pneumoniae
OmpR
host-pathogen interaction
epithelial cells
infection
dual RNA-seq
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03966-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.03966-23

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