Radiographic and α-fetoprotein response predict pathologic complete response to immunotherapy plus a TKI in hepatocellular carcinoma: a multicenter study

Radiographic and α-fetoprotein response predict pathologic complete response to immunotherapy plus a TKI in hepatocellular carcinoma: a multicenter study

Abstract Background Pathologic complete response (pCR) following preoperative systemic therapy is associated with improved outcomes after subsequent liver transplant/resection in hepatocellular carcinoma (HCC). However, the relationship between radiographic and histopathological response remains unc...

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Main Authors: Cheng Huang, Xiao-Dong Zhu, Ying-Hao Shen, Bin Xu, Dong Wu, Yuan Ji, Ling-Li Chen, Tian-Qiang Song, Wei Zhang, Zhi-Ming Zeng, Hua-Sheng Huang, Kui Wang, Lan-Qing Huang, Yong-Jun Chen, Yu-Chen Yang, Le-Du Zhou, Guo Long, Hai-Tao Zhao, Yun-Chao Wang, Ning-Ling Ge, Yi Chen, Chang-Jun Tan, Jian Zhou, Jia Fan, Hui-Chuan Sun
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Cancer
Subjects:
Tyrosine kinase inhibitor
Immunotherapy
Hepatocellular carcinoma
Conversion therapy
Pathologic complete response
Online Access:https://doi.org/10.1186/s12885-023-10898-z

Internet

https://doi.org/10.1186/s12885-023-10898-z

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