Insulin Oversecretion in MSG-Obese Rats is Related to Alterations in Cholinergic Muscarinic Receptor Subtypes in Pancreatic Islets

Insulin Oversecretion in MSG-Obese Rats is Related to Alterations in Cholinergic Muscarinic Receptor Subtypes in Pancreatic Islets

Background/ Aims: Impaired pancreatic beta cell function and insulin secretion/action are a link between obesity and type 2 diabetes, which are worldwide public health burdens. We aimed to characterize the muscarinic acetylcholine receptor (mAChR) M1-M4 subtypes in isolated pancreatic islets from pr...

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Bibliographic Details
Main Authors: Rosiane A. Miranda, Aryane R. Agostinho, Isis H. Trevenzoli, Luiz F. Barella, Claudinéia C. S. Franco, Amanda B. Trombini, Ananda Malta, Clarice Gravena, Rosana Torrezan, Paulo C. F. Mathias, Júlio C. de Oliveira
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
MSG-obese animals
Muscarinic receptor subtypes
Insulin secretion
Online Access:http://www.karger.com/Article/FullText/358677

Internet

http://www.karger.com/Article/FullText/358677

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