Synthesis of α,ω-bis-Mercaptoacyl Poly(alkyl oxide)s and Development of Thioether Cross-Linked Liposome Scaffolds for Sustained Release of Drugs

Synthesis of α,ω-bis-Mercaptoacyl Poly(alkyl oxide)s and Development of Thioether Cross-Linked Liposome Scaffolds for Sustained Release of Drugs

With the aim to develop novel scaffolds for the sustained release of drugs, we initially developed an easy approach for the synthesis of α,ω-homobifunctional mercaptoacyl poly(alkyl oxide)s. This was based on the esterification of the terminal hydroxyl groups of poly(alkyl oxide)s with suitably <...

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Bibliographic Details
Main Authors: Spyridon Mourtas, Georgios Kourmoulakis, Stavros Kremezis, Pavlos Klepetsanis, Sophia G. Antimisiaris
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Molecules
Subjects:
<i>S</i>-4-methoxytityl mercapto acids
α,ω-homofunctional mercaptoacyl poly(alkyl oxide)s
thia–Michael addition
thioether cross-linked liposomes
Online Access:https://www.mdpi.com/1420-3049/29/6/1312

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https://www.mdpi.com/1420-3049/29/6/1312

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