Reduced Maternal Circulating Cell‐Free Mitochondrial DNA Is Associated With the Development of Preeclampsia

Reduced Maternal Circulating Cell‐Free Mitochondrial DNA Is Associated With the Development of Preeclampsia

Background Circulating cell‐free mitochondrial DNA (ccf‐mtDNA) is a damage‐associated molecular pattern that reflects cell stress responses and tissue damage, but little is known about ccf‐mtDNA in preeclampsia. The main objectives of this study were to determine (1) absolute concentrations of ccf‐m...

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Bibliographic Details
Main Authors: Spencer C. Cushen, Contessa A. Ricci, Jessica L. Bradshaw, Talisa Silzer, Alexandra Blessing, Jie Sun, Zhengyang Zhou, Sabrina M. Scroggins, Mark K. Santillan, Donna A. Santillan, Nicole R. Phillips, Styliani Goulopoulou
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cell‐free DNA
DNase I
mitochondrial DNA
penalized regression analysis
preeclampsia
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.121.021726

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.121.021726

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