Superinfection Drives HIV Neutralizing Antibody Responses from Several B Cell Lineages that Contribute to a Polyclonal Repertoire

Superinfection Drives HIV Neutralizing Antibody Responses from Several B Cell Lineages that Contribute to a Polyclonal Repertoire

Summary: Eliciting broad and potent HIV-specific neutralizing antibody responses represents the holy grail of HIV vaccine efforts. Data from singly infected individuals with broad and potent plasma neutralizing activity targeting one epitope have guided our understanding of how these responses devel...

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Bibliographic Details
Main Authors: Katherine L. Williams, Bingjie Wang, Dana Arenz, James A. Williams, Adam S. Dingens, Valerie Cortez, Cassandra A. Simonich, Stephanie Rainwater, Dara A. Lehman, Kelly K. Lee, Julie Overbaugh
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718304431

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http://www.sciencedirect.com/science/article/pii/S2211124718304431

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