Suppression of allograft rejection by regulatory B cells induced via TLR signaling

Suppression of allograft rejection by regulatory B cells induced via TLR signaling

B lymphocytes have long been recognized for their critical contributions to adaptive immunity, providing defense against pathogens through cognate antigen presentation to T cells and Ab production. More recently appreciated is that B cells are also integral in securing self-tolerance; this has led t...

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Bibliographic Details
Main Authors: Kang Mi Lee, Qiang Fu, Guoli Huai, Kevin Deng, Ji Lei, Lisa Kojima, Divyansh Agarwal, Peter van Galen, Shoko Kimura, Naoki Tanimine, Laura Washburn, Heidi Yeh, Ali Naji, Charles G. Rickert, Christian LeGuern, James F. Markmann
Format: Article
Language:English
Published: American Society for Clinical investigation 2022-09-01
Series:JCI Insight
Subjects:
Immunology
Transplantation
Online Access:https://doi.org/10.1172/jci.insight.152213

Internet

https://doi.org/10.1172/jci.insight.152213

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