Gypenosides Synergistically Reduce the Extracellular Matrix of Hepatic Stellate Cells and Ameliorate Hepatic Fibrosis in Mice

Gypenosides Synergistically Reduce the Extracellular Matrix of Hepatic Stellate Cells and Ameliorate Hepatic Fibrosis in Mice

Liver fibrosis resulting from chronic liver damage is becoming one of the major threats to health worldwide. Active saponin constituents isolated from <i>Gynostemma pentaphyllum</i> were found to possess a protective effect in liver diseases. Here, we obtained a naturally abundant gypeno...

Full description

Bibliographic Details
Main Authors: Han Li, Hanghang Wang, Aiping Yang, Mingzhen Xue, Junyang Wang, Qi Lv, Jian Liu, Lihong Hu, Yinan Zhang, Xiachang Wang
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Molecules
Subjects:
gypenoside
liver fibrosis
PP2Cα
extracellular matrix
synergistic effect
Online Access:https://www.mdpi.com/1420-3049/28/14/5448

Internet

https://www.mdpi.com/1420-3049/28/14/5448

Similar Items