Major endothelial damage markers identified from hemadsorption filters derived from treated patients with septic shock – endoplasmic reticulum stress and bikunin may play a role

Major endothelial damage markers identified from hemadsorption filters derived from treated patients with septic shock – endoplasmic reticulum stress and bikunin may play a role

IntroductionIn septic patients the damage of the endothelial barrier is decisive leading to circulatory septic shock with disseminated vascular coagulation, edema and multiorgan failure. Hemadsorption therapy leads to rapid resolution of clinical symptoms. We propose that the isolation of proteins a...

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Bibliographic Details
Main Authors: Robin Kasper, Armando Rodriguez-Alfonso, Ludger Ständker, Sebastian Wiese, E. Marion Schneider
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
septic shock
endothelial damage
hemadsorption
oxidized DNA
bikunin/AMBP
SAA1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1359097/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1359097/full

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