Inhibition of p38 MAPK Signaling Regulates the Expression of EAAT2 in the Brains of Epileptic Rats

Inhibition of p38 MAPK Signaling Regulates the Expression of EAAT2 in the Brains of Epileptic Rats

Seizures induce the release of excitatory amino acids (EAAs) from the intracellular fluid to the extracellular fluid, and the released EAAs primarily comprise glutamic acid (Glu) and asparaginic acid (Asp). Glu neurotransmission functions via EAA transporters (EAATs) to maintain low concentrations o...

Full description

Bibliographic Details
Main Authors: Zhang Yang, Jing Wang, Changyin Yu, Ping Xu, Jun Zhang, Yan Peng, Zhong Luo, Hao Huang, Junwei Zeng, Zucai Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Neurology
Subjects:
epilepsy
glutamic acid
SB203580
excitatory amino acids
p38 mitogen-activated protein kinase
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00925/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2018.00925/full

Similar Items