New indazole-indolizine-triazine hybrid molecules with farnesyltransferase inhibitory activity

New indazole-indolizine-triazine hybrid molecules with farnesyltransferase inhibitory activity

A new series of indazole-indolizine-triazine hybrid molecules was obtained by [3 + 2] cycloaddition reaction between newly synthesized nitrogen ylides with indazole skeleton and previously reported dipolarophile 2‐ethynyl‐4,6‐dimethoxy‐1,3,5‐triazine and fully characterized. The biological evaluatio...

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Bibliographic Details
Main Authors: Liliana Ciurlă-Lucescu, Elena Bîcu, Dalila Belei, Alina Ghinet
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Results in Chemistry
Subjects:
Hybrid molecules
Indolizine
S-triazine
Indazole
Farnesyltransferase inhibitors
In vitro anticancer activity
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715624001474

Internet

http://www.sciencedirect.com/science/article/pii/S2211715624001474

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