Antigen Receptors Gene Analysis for Minimal Residual Disease Detection in Acute Lymphoblastic Leukemia: The Role of High Throughput Sequencing

The prognosis of adult acute lymphoblastic leukemia (ALL) is variable but more often dismal. Indeed, its clinical management is challenging, current therapies inducing complete remission in 65–90% of cases, but only 30–40% of patients being cured. The major determinant of treatment failure is relaps...

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Bibliographic Details
Main Authors: Pier Paolo Piccaluga, Stefania Paolini, Giuseppe Visani
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Hemato
Subjects:
Online Access:https://www.mdpi.com/2673-6357/4/1/4