Rechallenge of immune checkpoint inhibitors in a case with adverse events inducing myasthenia gravis

Rechallenge of immune checkpoint inhibitors in a case with adverse events inducing myasthenia gravis

The mechanism(s) of immune checkpoint inhibitor (ICI)-induced myasthenia gravis (MG), an immune-related adverse event (irAE) that is fatal and limits subsequent ICI use, remain unexplored. Here, through comparative genomic analysis, we identified a pathogenic p.S467C germline variant in SLC22A5 in a...

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Bibliographic Details
Main Authors: Jun Li, Wei Wang, Wei Zhang, Yang W Shao, Lu Shen, Liang Chen, Wen Gao, Jiali Xu, Jiani C Yin, Renhua Guo, Qianghu Wang, Lingxiang Wu, Shidai Jin, Xinyin Liu, Qixing Gong, Chunxiao Sun, Zidun Wang
Format: Article
Language:English
Published: BMJ Publishing Group 2022-11-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/10/11/e005970.full

Internet

https://jitc.bmj.com/content/10/11/e005970.full

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