Electron tomography of HIV-1 infection in gut-associated lymphoid tissue.

Critical aspects of HIV-1 infection occur in mucosal tissues, particularly in the gut, which contains large numbers of HIV-1 target cells that are depleted early in infection. We used electron tomography (ET) to image HIV-1 in gut-associated lymphoid tissue (GALT) of HIV-1-infected humanized mice, t...

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Bibliographic Details
Main Authors: Mark S Ladinsky, Collin Kieffer, Gregory Olson, Maud Deruaz, Vladimir Vrbanac, Andrew M Tager, Douglas S Kwon, Pamela J Bjorkman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3907528?pdf=render