Humanization for neurological disease modeling: A roadmap to increase the potential of Drosophila model systems

Abstract Neuroscience and neurology research is dominated by experimentation with rodents. Around 75% of neurology disease‐associated genes have orthologs in Drosophila melanogaster, the fruit fly amenable to complex neurological and behavioral investigations. However, non‐vertebrate models includin...

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Bibliographic Details
Main Author: Vladimir L. Katanaev
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Animal Models and Experimental Medicine
Subjects:
Online Access:https://doi.org/10.1002/ame2.12322