Efficacy of the combination of amphotericin B and echinocandins against Candida auris in vitro and in the Caenorhabditis elegans host model

Efficacy of the combination of amphotericin B and echinocandins against Candida auris in vitro and in the Caenorhabditis elegans host model

ABSTRACT The multidrug-resistant Candida auris is a global health emergency, being responsible for outbreaks of invasive candidiasis worldwide. Limited effective therapeutic options make it difficult to treat this emerging pathogen. In this context, combinations of different antifungal drugs are con...

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Bibliographic Details
Main Authors: Ainara Hernando-Ortiz, Elena Eraso, Nerea Jauregizar, Piet W.J. de Groot, Guillermo Quindós, Estibaliz Mateo
Format: Article
Language:English
Published: American Society for Microbiology 2024-01-01
Series:Microbiology Spectrum
Subjects:
Candidiasis
antifungal activity
drug combinations
Caenorhabditis elegans model
Candida auris
amphotericin B
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02086-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.02086-23

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