A shape-adjusted ellipse approach corrects for varied axonal dispersion angles and myelination in primate nerve roots
Abstract Segmentation of axons in light and electron micrographs allows for quantitative high-resolution analysis of nervous tissues, but varied axonal dispersion angles result in over-estimates of fiber sizes. To overcome this technical challenge, we developed a novel shape-adjusted ellipse (SAE) d...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-02-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-82575-9 |