Effects of dimethyl sulfoxide on apolipoprotein A-I in the human hepatoma cell line, HepG2

Exposure of HepG2 cells to 1٪ (v/v) dimethyl sulfoxide (DMSO), an effective free radical scavenger, for 24 h resulted in a 2-fold increase in the levels of apolipoprotein (apo) A-I mRNA and secreted protein, with no significant change in apoA-II, apoB, and apoE mRNA and protein levels. The induction...

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Bibliographic Details
Main Authors: S P Tam, X Zhang, C Cuthbert, Z Wang, T Ellis
Format: Article
Language:English
Published: Elsevier 1997-10-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752037139X