The Aurora kinase inhibitor AT9283 inhibits Burkitt lymphoma growth by regulating Warburg effect

Objective To investigate the effect of the kinase inhibitor AT9283 on Burkitt lymphoma (BL) cells and elucidate the underlying mechanisms. Methods The effect of AT9283 on the proliferation of BL cell lines was tested using the MTT assay. Apoptosis and cell cycle were measured by flow cytometry. The...

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Bibliographic Details
Main Authors: Kaiming Jiang, Lihong Bai, Canfei Wang, Xiang Xiao, Zhao Cheng, Hongling Peng, Sufang Liu
Format: Article
Language:English
Published: PeerJ Inc. 2023-12-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/16581.pdf