APAF1‐Binding Long Noncoding RNA Promotes Tumor Growth and Multidrug Resistance in Gastric Cancer by Blocking Apoptosome Assembly

APAF1‐Binding Long Noncoding RNA Promotes Tumor Growth and Multidrug Resistance in Gastric Cancer by Blocking Apoptosome Assembly

Abstract Chemotherapeutics remain the first choice for advanced gastric cancers (GCs). However, drug resistance and unavoidable severe toxicity lead to chemotherapy failure and poor prognosis. Long noncoding RNAs (lncRNAs) play critical roles in tumor progression in many cancers, including GC. Here,...

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Bibliographic Details
Main Authors: Qiang Wang, Chen Chen, Xiao Xu, Chuanjun Shu, Changchang Cao, Zhangding Wang, Yao Fu, Lei Xu, Kaiyue Xu, Jiawen Xu, Anliang Xia, Bo Wang, Guifang Xu, Xiaoping Zou, Ruibao Su, Wei Kang, Yuanchao Xue, Ran Mo, Beicheng Sun, Shouyu Wang
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:Advanced Science
Subjects:
ABL
apoptotic protease‐activating factor 1 (APAF1)
apoptosis
drug resistance
gastric cancer
IGF2BP1
Online Access:https://doi.org/10.1002/advs.202201889

Internet

https://doi.org/10.1002/advs.202201889

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