Age-Dependent and Pathway-Specific Bimodal Action of Nicotine on Synaptic Plasticity in the Hippocampus of Mice Lacking the miR-132/212 Genes

Age-Dependent and Pathway-Specific Bimodal Action of Nicotine on Synaptic Plasticity in the Hippocampus of Mice Lacking the miR-132/212 Genes

Nicotine addiction develops predominantly during human adolescence through smoking. Self-administration experiments in rodents verify this biological preponderance to adolescence, suggesting evolutionary-conserved and age-defined mechanisms which influence the susceptibility to nicotine addiction. T...

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Bibliographic Details
Main Authors: Tamara Stojanovic, David Velarde Gamez, Gabor Jorrid Schuld, Daniel Bormann, Maureen Cabatic, Pavel Uhrin, Gert Lubec, Francisco J. Monje
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cells
Subjects:
miR-132/212
nicotine
ACh
hippocampus
LTP
Online Access:https://www.mdpi.com/2073-4409/11/2/261

Internet

https://www.mdpi.com/2073-4409/11/2/261

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