EDTA stabilizes the concentration of platelet-derived extracellular vesicles during blood collection and handling

EDTA stabilizes the concentration of platelet-derived extracellular vesicles during blood collection and handling

Citrate is the recommended anticoagulant for studies on plasma extracellular vesicles (EVs). Because citrate incompletely blocks platelet activation and the release of platelet-derived EVs, we compared EDTA and citrate in that regard. Blood from healthy individuals (n = 7) was collected and incubate...

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Bibliographic Details
Main Authors: Naomi C. Buntsma, Aleksandra Gąsecka, Yvo B.W.E.M. Roos, Ton G. van Leeuwen, Edwin van der Pol, Rienk Nieuwland
Format: Article
Language:English
Published: Taylor & Francis Group 2022-07-01
Series:Platelets
Subjects:
anticoagulants
biomarkers
blood platelets
extracellular vesicles
flow cytometry
Online Access:http://dx.doi.org/10.1080/09537104.2021.1991569

Internet

http://dx.doi.org/10.1080/09537104.2021.1991569

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