The S341P mutant MYOC renders the trabecular meshwork sensitive to cyclic mechanical stretch

The trabecular meshwork (TM) plays an essential role in the circulation of aqueous humor by sensing mechanical stretch. The balance between the outflow and inflow of aqueous humor is critical in regulating intraocular pressure (IOP). A dysfunctional TM leads to resistance to the outflow of aqueous h...

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Bibliographic Details
Main Authors: Xuejing Yan, Shen Wu, Qian Liu, Yufei Teng, Ningli Wang, Jingxue Zhang
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024131684