The S341P mutant MYOC renders the trabecular meshwork sensitive to cyclic mechanical stretch
The trabecular meshwork (TM) plays an essential role in the circulation of aqueous humor by sensing mechanical stretch. The balance between the outflow and inflow of aqueous humor is critical in regulating intraocular pressure (IOP). A dysfunctional TM leads to resistance to the outflow of aqueous h...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-09-01
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Series: | Heliyon |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024131684 |