Sialylated human milk oligosaccharides prevent intestinal inflammation by inhibiting toll like receptor 4/NLRP3 inflammasome pathway in necrotizing enterocolitis rats

Sialylated human milk oligosaccharides prevent intestinal inflammation by inhibiting toll like receptor 4/NLRP3 inflammasome pathway in necrotizing enterocolitis rats

Abstract Background Necrotizing enterocolitis (NEC) remains a fatal gastrointestinal disorder in neonates and has very limited therapeutic options. Sialylated human milk oligosaccharides (SHMOs) improve pathological changes in experimental NEC models. The objectives of this study were to investigate...

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Bibliographic Details
Main Authors: Wenting Zhang, Jingqiu He-Yang, Wenjuan Tu, Xiaoying Zhou
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Nutrition & Metabolism
Subjects:
Necrotizing enterocolitis
Human milk oligosaccharide
Neonates
Nod-like receptor pyrin domain-containing 3
Inflammation
Online Access:https://doi.org/10.1186/s12986-020-00534-z

Internet

https://doi.org/10.1186/s12986-020-00534-z

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