Formulation and in vitro evaluation of taste-masked oro-dispersible dosage form of diltiazem hydrochloride

Diltiazem hydrochloride is a calcium channel blocker generally indicated for the treatment of angina and hypertension, and it is extensively metabolized due to the hepatic metabolism. Formulation of diltiazem hydrochloride into an oro-dispersible dosage form can provide fast relief with higher bioav...

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Bibliographic Details
Main Authors: Swati Changdeo Jagdale, Vaibhav Uttam Gawali, Bhanudas Shankar Kuchekar, Aniruddha Rajaram Chabukswar
Format: Article
Language:English
Published: Universidade de São Paulo 2011-12-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000400028