Dual activities of a silencing information regulator complex in yeast transcriptional regulation and DNA‐damage response

Abstract The Saccharomyces cerevisiae silencing information regulator (SIR) complex contains up to four proteins, namely Sir1, Sir2, Sir3, and Sir4. While Sir2 encodes a NAD‐dependent histone deacetylase, other SIR proteins mainly function as structural and scaffold components through physical inter...

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Bibliographic Details
Main Authors: Josephine Rybchuk, Wei Xiao
Format: Article
Language:English
Published: Wiley 2024-06-01
Series:mLife
Subjects:
Online Access:https://doi.org/10.1002/mlf2.12108