Dual activities of a silencing information regulator complex in yeast transcriptional regulation and DNA‐damage response
Abstract The Saccharomyces cerevisiae silencing information regulator (SIR) complex contains up to four proteins, namely Sir1, Sir2, Sir3, and Sir4. While Sir2 encodes a NAD‐dependent histone deacetylase, other SIR proteins mainly function as structural and scaffold components through physical inter...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2024-06-01
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Series: | mLife |
Subjects: | |
Online Access: | https://doi.org/10.1002/mlf2.12108 |