CD40-TRAF Signaling Upregulates CX3CL1 and TNF-α in Human Aortic Endothelial Cells but Not in Retinal Endothelial Cells.

CD40, CX3CL1 and TNF-α promote atheroma and neointima formation. CD40 and TNF-α are also central to the development of diabetic retinopathy while CX3CL1 may play a role in the pathogenesis of this retinopathy. The purpose of this study was to examine whether CD40 ligation increases CX3CL1 and TNF-α...

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Détails bibliographiques
Auteurs principaux: Jennifer A Greene, Jose-Andres C Portillo, Yalitza Lopez Corcino, Carlos S Subauste
Format: Article
Langue:English
Publié: Public Library of Science (PLoS) 2015-01-01
Collection:PLoS ONE
Accès en ligne:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0144133&type=printable