Unbiased analysis of TCRα/β chains at the single-cell level in human CD8+ T-cell subsets.

T-cell receptor (TCR) α/β chains are expressed on the surface of CD8(+) T-cells and have been implicated in antigen recognition, activation, and proliferation. However, the methods for characterization of human TCRα/β chains have not been well established largely because of the complexity of their s...

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Bibliographic Details
Main Authors: Xiaoming Sun, Masumichi Saito, Yoshinori Sato, Takayuki Chikata, Takuya Naruto, Tatsuhiko Ozawa, Eiji Kobayashi, Hiroyuki Kishi, Atsushi Muraguchi, Masafumi Takiguchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22792299/pdf/?tool=EBI