A SIV molecular clone that targets the CNS and induces neuroAIDS in rhesus macaques.

Despite effective control of plasma viremia with the use of combination antiretroviral therapies (cART), minor cognitive and motor disorders (MCMD) persist as a significant clinical problem in HIV-infected patients. Non-human primate models are therefore required to study mechanisms of disease progr...

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Bibliographic Details
Main Authors: Kenta Matsuda, Nadeene E Riddick, Cheri A Lee, Sarah B Puryear, Fan Wu, Bernard A P Lafont, Sonya Whitted, Vanessa M Hirsch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-08-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1006538&type=printable