Zinc dysregulation in cancers and its potential as a therapeutic target

Zinc is an essential element and serves as a structural or catalytic component in many proteins. Two families of transporters are involved in maintaining cellular zinc homeostasis: the ZIP (SLC39A) family that facilitates zinc influx into the cytoplasm, and the ZnT (SLC30A) family that facilitates z...

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Bibliographic Details
Main Authors: Jie Wang, Huanhuan Zhao, Zhelong Xu, Xinxin Cheng
Format: Article
Language:English
Published: China Anti-Cancer Association 2020-08-01
Series:Cancer Biology & Medicine
Subjects:
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/1669