KDM6B promotes gastric carcinogenesis and metastasis via upregulation of CXCR4 expression

Abstract KDM6B (Lysine-specific demethylase 6B) is a histone lysine demethyltransferase that plays a key role in many types of cancers. However, its potential role in gastric cancer (GC) remains unclear. Here, we focused on the clinical significance and potential role of KDM6B in GC. We found that t...

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Bibliographic Details
Main Authors: Fen Liu, Yue Wang, Zongcheng Yang, Xiujie Cui, Lixin Zheng, Yue Fu, Wei Shao, Lu Zhang, Qing Yang, Jihui Jia
Format: Article
Language:English
Published: Nature Publishing Group 2022-12-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05458-5