SARS-CoV-2-encoded small RNAs are able to repress the host expression of SERINC5 to facilitate viral replication

SARS-CoV-2-encoded small RNAs are able to repress the host expression of SERINC5 to facilitate viral replication

Serine incorporator protein 5 (SERINC5) is a key innate immunity factor that operates in the cell to restrict the infectivity of certain viruses. Different viruses have developed strategies to antagonize SERINC5 function but, how SERINC5 is controlled during viral infection is poorly understood. Her...

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Bibliographic Details
Main Authors: Salvador Meseguer, Mari-Paz Rubio, Begoña Lainez, Beatriz Pérez-Benavente, Raúl Pérez-Moraga, Sergio Romera-Giner, Francisco García-García, Olalla Martinez-Macias, Antonio Cremades, Francisco J. Iborra, Oscar Candelas-Rivera, Fernando Almazan, Enric Esplugues
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Microbiology
Subjects:
SARS-CoV-2
viral miRNAs
SERINC5
MAVS
innate immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1066493/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1066493/full

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