Physiological Sensing of Carbon Dioxide/Bicarbonate/pH via Cyclic Nucleotide Signaling

Carbon dioxide (CO2) is produced by living organisms as a byproduct of metabolism. In physiological systems, CO2 is unequivocally linked with bicarbonate (HCO3−) and pH via a ubiquitous family of carbonic anhydrases, and numerous biological processes are dependent upon a mechanism for sensing the le...

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Bibliographic Details
Main Authors: Lonny R. Levin, Jochen Buck
Format: Article
Language:English
Published: MDPI AG 2011-02-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/11/2/2112/