Exploring roles of the chitinase ChiC in modulating Pseudomonas aeruginosa virulence phenotypes

Exploring roles of the chitinase ChiC in modulating Pseudomonas aeruginosa virulence phenotypes

ABSTRACT Chitinases are ubiquitous enzymes involved in biomass degradation and chitin turnover in nature. Pseudomonas aeruginosa (PA), an opportunistic human pathogen, expresses ChiC, a secreted glycoside hydrolase 18 family chitinase. Despite speculation about ChiC’s role in PA disease pathogenesis...

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Bibliographic Details
Main Authors: Per Kristian Thorén Edvardsen, Fatemeh Askarian, Raymond Zurich, Victor Nizet, Gustav Vaaje-Kolstad
Format: Article
Language:English
Published: American Society for Microbiology 2024-07-01
Series:Microbiology Spectrum
Subjects:
Pseudomonas aeruginosa
chitinase
GH18
virulence
biofilm
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00546-24

Internet

https://journals.asm.org/doi/10.1128/spectrum.00546-24

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